Conolidine’s analgesic consequences stem from its interaction with non-opioid pain pathways. In contrast to opioids, which bind to µ-opioid receptors from the central anxious system, conolidine modulates alternate molecular targets. A Science Improvements research observed that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide avail... https://prbookmarkingwebsites.com/story26805565/alternative-natural-pain-relief-to-replace-traditional-painkillers-an-overview