Inborn defects of the tricarboxylic acid (TCA) cycle enzymes have been known for more than twenty years. Until recently. only recessive mutations were described which. although resulted in severe multisystem syndromes. https://www.roneverhart.com/Western-Digital-Ultrastar-DC-HC550-WUH721816ALE6L0-0F38460-16TB-7-2K-RPM-SATA-6Gb-s-512e-ISE-3-5in-Hard-Drive/