Pentobarbital will lower the extent or outcome of artemether/lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration with strong CYP3A4 inducers can lead to decreased serum concentrations and lack of antimalarial efficacy pentobarbital will minimize the level or influence of fentanyl by affecting hepatic/intestinal enzyme ... https://muhammadd220qfv7.weblogco.com/profile