Chemotherapy was potentiated by E7449 and solitary agent had important antitumor exercise in BRCA-deficient xenografts. Additionally, E7449 inhibited Wnt/β-catenin signaling in colon most cancers mobile strains, possible through TNKS inhibition. Per this probability, E7449 stabilized axin and TNKS proteins causing β-catenin de-stabilization and significantly altered expression of Wnt ... https://andrexpzgk.jiliblog.com/86958822/about-apigenin