8 Thus, the flexibility of tapentadol to keep action within the absence of MOR exercise suggests It's not necessarily adequate to label it just ‘an opioid’ without having acknowledging the major noradrenergic part to its actions. Recently, Diffuse Noxious Inhibitory Controls (DNIC), an endogenous inhibitory process mediated by descending controls, https://rylanovslf.blogsidea.com/35110048/the-basic-principles-of-tapentadol